HSV-I IgG Rapid Test

HSV-I IgG Rapid Test

Type: Uncut Sheet

Brand: Bio-mapper

Catalog:RT0321

Specimen:WB/S/P

Sensitivity:94.20%

Specificity:99.50%

Herpes simplex virus (HSV) is a kind of common pathogen that seriously endangers human health and causes skin diseases and venereal diseases. There are two serotypes of HSV: HSV-1 and HSV-2. HSV-1 mainly causes infection above the waist, and the most common infection sites are the mouth and lips; HSV-2 mainly causes infection below the waist. HSV-1 can cause not only primary infection, but also latent infection and recurrence. Primary infection most often causes herpetic keratoconjunctivitis, oropharyngeal herpes, cutaneous herpetic eczema and encephalitis. The latency sites were superior cervical ganglion and trigeminal ganglion. HSV-2 is mainly transmitted through direct close contact and sexual contact. The latent site of the virus is the sacral ganglion. After stimulation, the latent virus can be activated, causing recurrent infection. It is difficult to isolate virus, detect PCR and antigen in such patients, while antibodies (IgM and IgG antibodies) in serum can be detected.

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Herpes simplex is one of the common sexually transmitted diseases, mainly caused by HSV-2 infection. Serological antibody test (including IgM antibody and IgG antibody test) has a certain sensitivity and specificity, which is not only applicable to patients with symptoms, but also can detect patients without skin lesions and symptoms. After the initial infection with HSV-2, the antibody in the serum rose to the peak within 4-6 weeks. The specific IgM antibody produced in the early stage was transient, and the appearance of IgG was later and lasted longer. In addition, some patients have IgG antibodies in their bodies. When they relapse or re infect, they do not produce IgM antibodies. Therefore, IgG antibodies are generally detected.
HSV IgG titer ≥ 1 ∶ 16 is positive. It suggests that HSV infection continues. The highest titer was determined as the highest dilution of serum with at least 50% infected cells showing obvious green fluorescence. The titer of IgG antibody in double serum is 4 times or more, indicating the recent infection of HSV. The positive test of herpes simplex virus IgM antibody indicates that herpes simplex virus has recently been infected.